Anomeric Proton and Carbon (H1-C1) NMR Chemical Shifts of Antigenic Mannans Obtained from Pathogenic Yeast &i&Candida tropicalis&/i&

摘要

On two dimensional maps of ~(1)H-~(13)C correlation spectroscopy (H-C COSY) analysis for the mannan of Candida tropicalis , nine cross peaks of anomeric proton and carbon were useful for the purpose of obtaining information on the chemical structure of this molecule. Namely, the mannans was comb-like structure constructed with the linear α -1,6-linked polymannnosyl backbone and several oligomannnosyl side chains composed of α -1,2-, α -1,3-, and β -1,2-linkages. Therefore, in the structural investigation of comb-like mannan, two-dimensional H-C COSY analysis is as useful as two-dimensional nuclear Hartmann-Hahn (HOHAHA) analysis.