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首页> 外文期刊>Nucleic acids research >Oviz-Bio: a web-based platform for interactive cancer genomics data visualization
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Oviz-Bio: a web-based platform for interactive cancer genomics data visualization

机译:Oviz-Bio:基于Web的交互式癌症基因组学数据可视化平台

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Genetics data visualization plays an important role in the sharing of knowledge from cancer genome research. Many types of visualization are widely used, most of which are static and require sufficient coding experience to create. Here, we present Oviz-Bio, a web-based platform that provides interactive and real-time visualizations of cancer genomics data. Researchers can interactively explore visual outputs and export high-quality diagrams. Oviz-Bio supports a diverse range of visualizations on common cancer mutation types, including annotation and signatures of small scale mutations, haplotype view and focal clusters of copy number variations, split-reads alignment and heatmap view of structural variations, transcript junction of fusion genes and genomic hotspot of oncovirus integrations. Furthermore, Oviz-Bio allows landscape view to investigate multi-layered data in samples cohort. All Oviz-Bio visual applications are freely available at https://bio.oviz.org/.
机译:遗传学数据可视化在癌症基因组研究中的知识中起着重要作用。许多类型的可视化被广泛使用,其中大多数是静态的并且需要足够的编码体验来创建。在这里,我们呈现Oviz-Bio,是一种基于Web的平台,提供癌症基因组学数据的交互式和实时可视化。研究人员可以交互方式探索视觉输出和出口高质量图。 Oviz-Bio支持常见癌症突变类型的各种可视化,包括小规模突变的注释和签名,单倍型视图和拷贝数变异的焦点簇,分裂读取对准和结构变异的热图视图,融合基因的转录结符和神经病毒整合的基因组热点。此外,Oviz-Bio允许景观视图调查样本队列中的多层数据。所有OVIZ-BIO Visual Applications都可以在https://bio.oviz.org/中自由使用。

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