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Testicular cancer stem cell hypothesis - diagnostic and therapeutic implications

机译:睾丸癌干细胞假设 - 诊断和治疗意义

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Testicular cancer is an uncommon malignancy in men and is curable in most instances. There is marked geographical variation with age-standardized rate (ASR) per 100,000 ranging from 4.6 in developed countries to 0.8 in developing countries 1 . The incidence of testicular cancer is highest in Western and Northern Europe, Australia, and North America, while the lowest incidence is in Asia and Africa 2 . Despite its low overall incidence, it is the most common cancer in young men, in the third or fourth decade of life 3 . The incidence of testicular cancer has been increasing over the past four decades, while mortality rate has been decreasing in most European countries 4–6 . Over 71,000 new testicular cancer cases and 9,500 deaths are estimated to occur worldwide in 2018 7 .
机译:睾丸癌是男性罕见的恶性肿瘤,在大多数情况下可固化。在发达国家4.6中,每10万人的年龄标准化率(ASR)的地理变化标志着为0.8岁。西部和北欧和北美睾丸癌的发病率最高,而最低的发病率是亚洲和非洲2。尽管其总体发病率低,但它是年轻人中最常见的癌症,在生命的第三或第四十年中。睾丸癌的发生率在过去的四十年中一直在增加,而大多数欧洲国家的死亡率一直在减少4-6。估计2018年7月7日以上超过71,000例新的睾丸癌病例和9,500人死亡。

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