Hemostatic powders are topical agents used in thera- peutic and potentially prophylactic control of GI bleeding. 1 When effectively applied to the site of bleeding, the powder allows for better visualization of the area and subsequent definitive therapy. These powders are generally composed of small mineral granules that stimulate hemostasis. In the United States, the inorganic powder TC-325 (Hemospray; Cook Medical, Bloomington, Ind, USA) was the first to be brought onto the market. 2 It was approved by the United States Food and Drug Administration in May 2018 for treatment of nonvariceal bleeding. 3 It is currently not approved for routine management of acute variceal bleeding because of the theoretical risk of venous thromboembolism.
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