Interobserver variability in colorectal cancer and the 2016 ITBCC concensus

摘要

To the editor: We read with great interest the work of Lugli et al. [1] on the fascinating subject of tumor budding (TB), an independent and robust prognostic factor in colorectal cancer but without a standardized method for its evaluation until consensus in 2016. However, there is no information on interobserver variability applying the consensus, and we have some concerns.