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THE EFFECTIVENESS OF GLUCOMANNAN AND NANO ACTIVATED-CARBON AS HYPERCHOLESTEROL-LOWERING AGENTS

机译:葡糖胺和纳米活性炭作为高胆固醇降解剂的有效性

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Porang (konjac) plants have long been used as a food source and traditional medicine. Glucomannan derived from porang has been utilised for various uses such as antidiabetic and antihypercholesterolemia agent. This paper studies the mixture of porang flour and nano activated-carbon and its effect on the cholesterol activity of rats. The mixture of porang and activated carbon were subjected to test for male Sprague Dawley rats to test the antihypercholesterolemia activity. The result showed that concerted anticholesterol activity of porang and nano activated-carbon revealed the cholesterol level decreases in rat's blood. However, the different treatments of unleached and leached porang either leached porang and nano activated-carbon applied in the experiments showed that the levels of cholesterol decrease were slightly different (16–18%). Low glucomannan content as the alleged anticholesterol agent was regarded quite effective in lowering the cholesterol level in rat's blood and comparable with those of simvastatin which achieved 18% reduction. Therefore, it indicates potential utilisation as a functional food for a cholesterol-lowering agent. The involvement of activated carbon in the alleged anticholesterol agent (leached porang flour) did little in enhancing the cholesterol level decrease in rat's blood. The glucomannan in both leached porang flour and leached porang flour nano activated-carbon shows potential utilisation as an anticholesterol agent. Yet, raw (unleached) porang is prospectively potential as a functional food for cholesterol-lowering.
机译:Porang(Konjac)植物长期被用作食物来源和传统医学。源于Porang的葡甘甘甘油已用于各种用途,如抗糖尿病和抗高胆固醇血症剂。本文研究了突粉和纳米活性炭的混合物及其对大鼠胆固醇活性的影响。对Porang和活性炭的混合物进行雄性Sprague Dawley大鼠测试,以测试抗高胆固醇血症活性。结果表明,Porang和纳米活化碳的齐铬物醇活性显示大鼠血液中的胆固醇水平降低。然而,在实验中浸出的Porang和纳米活化 - 碳的不同治疗潜水和纳米活化碳的浸出和浸出的Porang略微不同(16-18%)。随着所谓的抗胆固醇剂的葡糖胺含量低,视为降低大鼠血液中的胆固醇水平并与辛伐他汀的胆固醇水平相比,其达到18%的减少。因此,它表明潜在的利用作为降胆固醇降低剂的功能性食品。活性炭在涉嫌抗胆固醇剂(浸出的浮孔面粉)中的参与在提高大鼠血液中的胆固醇水平降低几乎没有。浸出的Porang面粉中的葡甘露霉甘油甘蓝胺含有浸出的Porang面粉纳米活化碳显示出潜在的利用作为抗胆固醇剂。然而,原始(无申请)Porang是前瞻性的胆固醇降低功能食品。

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