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ABO, Rh, and kell blood group antigen frequencies in blood donors at the tertiary care hospital of Northwestern India

机译:印度西北三级护理医院的献血者中ABO,RH和KELL血型抗原频率

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Background: This study was performed to provide information on frequencies of ABO, Rh & Kell antigens/alleles, phenotype in blood donors at Blood Bank, SMS hospital, Jaipur and to compare them with other races. Methodology: This study was conducted on blood donors from April 2016 to March 2017 using a fully automated system for ABO,Rh & Kell typing of blood cells. D, C, c, E, e & K antigens were typed using monoclonal antisera from Immucor The data were collected and calculations done to determine the antigen/allele, phenotype. The chi square test 3 degree of freedom with P 0.001 (S) was used for comparisons between the results of our study and those of other studies. Results: A total of 8067 donors were included in this study. Maximum donors was of B blood group (39.4%) of age 18-25(35.5%) with 60-69kg weight (65%). The most common Rh antigen found was e(99.3%) followed by D (93.8%), C (85.4%), c (60.1%), E (17.5%). R1r (DCCee) was the most common phenotype in our study (39.5%). Kell (K ) antigen was present in 2.7% of donors. Conclusion: We have determined the prevalence of Rh antigens and Rh phenotypes in blood donor at our hospital and derived the allele frequencies in the same population.
机译:背景:本研究进行了关于ABO,RH和KELL抗原/等位基因的频率,血库,斋浦尔的献血者中型的信息,并将其与其他种族进行比较。方法论:本研究于2016年4月至2017年3月对献血者进行了使用全自动系统,用于ABO,RH和Kell键入血细胞。 D,C,C,E,E&k抗原使用从Immucer的单克隆抗血清类型进行类型,并收集数据并进行计算以确定抗原/等位基因,表型。志方检测3种具有P <0.001(S)的自由度用于我们研究结果与其他研究结果之间的比较。结果:本研究共纳入了8067名捐赠者。 18-25岁(35.5%)的最大供体为18-25岁(35.5%),重量为60-69kg(65%)。发现最常见的Rh抗原是E(99.3%),然后是D(93.8%),C(85.4%),C(60.1%),E(17.5%)。 R1R(DCCEE)是我们研究中最常见的表型(39.5%)。 Kell(k)抗原以2.7%的供体存在。结论:我们确定了我们医院献血者血液供体中的Rh抗原和RH表型的患病率,并在同一人群中衍生出等位基因频率。

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