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首页> 外文期刊>JPRAS Open >The successful use of a bespoke OssDsign cranial plate to reconstruct an occipital defect following excision of a recurrent epithelioid sarcoma
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The successful use of a bespoke OssDsign cranial plate to reconstruct an occipital defect following excision of a recurrent epithelioid sarcoma

机译:成功使用定制OSSSign颅骨,在切除复发性上皮肉瘤切除后重建枕骨缺陷

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A cranioplasty has a number of known associated complications including infection for non-biological implants and bone flap resorption where autologous grafts are used. In recent years, bioactive ceramic cranial implants have been developed as a new reconstructive option. The OssDsign cranial plate (OssDsign AB, Uppsala, Sweden) was first introduced in 2010 and consists of an interconnected mosaic of hydroxyapatite tiles mounted onto a 3D-printed titanium mesh. Each tile is composed of a monetite, beta-calcium pyrophosphate, beta-tricalcium phosphate and brushite compound designed to mimic the process of coupled bone formation once implanted.This case presents a patient's journey from diagnosis of an epithelioid sarcoma over the posterior scalp and its management in the following 7 years. Initial excision of the lesion was reconstructed with a tissue expander and local rotational flap. Recurrence of the disease 3 years later was treated with a course of radical radiotherapy. Persistent osteomyelitis over the next 3 years resulted in chronic ulceration and exposed bone in the treated area. As the first part of a 3-stage treatment plan, two separate tissue expanders became infected. The multidisciplinary team therefore chose to use a bespoke OssDsign cranial plate combined with a deep inferior epigastric perforator (DIEP) free flap to provide a definitive single operative solution. The advantages over other reconstruction options include that the plate can be removed should further excision be required, greater potential for long-term integration with surrounding tissues and the ability to be soaked in antibiotic to reduce the risk of infection.
机译:颅骨成形术具有许多已知的相关并发症,包括用于非生物植入物的感染和使用自体移植物的骨翼片吸收。近年来,生物活性陶瓷颅植入物已成为新的重建选项。首次在2010年首次推出了OSSDSign颅盘(Ossdsign Ab,乌普萨拉,瑞典,并由安装在3D印刷的钛网上的羟基磷灰石瓷砖的互连马赛克组成。每个瓷砖由甘露酯,β-磷酸钙,磷酸β-磷酸钙,β-磷酸钙和石棉化合物组成,旨在模仿偶然骨形成的过程。本案例呈现了患者从后头皮上的上皮肌肉诊断患者的旅程管理层在以下7年。用组织扩展器和局部旋转翼片重建病变的初始切除。 3年后疾病的再次进行治疗,并通过一种激进的放射治疗治疗。未来3年持续骨髓炎导致治疗区域中的慢性溃疡和暴露骨骼。作为3阶段治疗计划的第一部分,感染了两个单独的组织扩展器。因此,多学科团队选择使用定制的OSSign颅板,与深劣质的外延穿孔器(Diep)自由翼片结合,以提供一个明确的单个操作溶液。其他重建选项的优点包括可以去除板应该需要进一步切除,并且具有与周围组织的长期集成的潜力以及浸入抗生素中以降低感染风险的能力。

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