SAPHO syndrome associated with acne conglobata successfully treated with etanercept

摘要

A 42-year-old Taiwanese male presented to our derma- tology department with complaint of chronic acne on the face, back and buttocks with severe sinus tracts and depressed scar formation for 20 years (Fig. 1A). Long-term oral minocycline provided some relief, but new crops of lesions continued to develop periodically. He started to suffer from intermittent chest pain and palpitation during the past 5 years. Repeated 24-hour-electrocardiography monitoring and echocardiography were unremarkable. In addition, episodic polyarthralgia over the bilateral tempo- romandibular joint, left shoulder, and left ankle were noted in recent years. Laboratory studies revealed a mild.