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Enterococci from breast-fed infants exert higher antibacterial effects than those from adults: A comparative study

机译:来自母乳喂养婴儿的肠球菌比来自成年人的抗菌效果更高:比较研究

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Enterococci are members of human gut microbiota which their colonization has been demonstrated even before birth. This indicates their importance in infant health. As this population is dynamic and varies with age, this study was designed to assess and compare the antibacterial effects of enterococci from breast-fed infants and those from adults. Fecal isolates of enterococci were isolated from infants and healthy adults and were identified to the species level by phenotypic and genotypic Method s. Further, they were evaluated for their potential to exert antibacterial effect against ten standard bacterial strains using bilayer spot test. Of a total of eighty-nine recovered enterococcal isolates, Enterococcus faecium and E. faecalis were the most common species (98%) and showed inhibitory effects at least against one indicator strain. Comparison between isolates from two studied groups showed that isolates from neonates introduced significantly higher growth inhibitory effects against six indicator strains (P?
机译:肠球菌是人体肠道微生物群的成员,其殖民化甚至在出生前也证明。这表明他们对婴儿健康的重要性。由于这种人口是动态的,随着年龄的增长而变化,本研究旨在评估和比较肠球菌对母乳喂养婴儿的抗菌作用和成人的抗菌作用。从婴儿和健康的成人分离肠内分离株的粪便分离株,并通过表型和基因型方法鉴定到物种水平。此外,他们评估了它们使用双层点测试的10个标准细菌菌株发挥抗菌作用的潜力。总共八十九次恢复的肠球菌分离物,肠球菌粪便,粪便粪便是最常见的物种(98%),并且至少表现出至少针对一个指示剂菌株的抑制作用。来自两个研究组的分离物之间的比较显示,Neonates的分离株对六个指示剂菌株引入显着较高的生长抑制作用(P?<β05),这些效果通常归因于E.粪便分离株。此外,针对李斯特菌单核细胞增生观察到最高的生长抑制效果。肠球菌在人类微生物群中的抗菌作用。这些生物在新生儿期内的有益作用表明肠内婴儿肠内婴儿的潜在潜力。

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