Phenotypic Features of Red Blood Cell Antigens in Uzbekistan

摘要

The aim of the study was to study the antigenic properties of red blood cells in healthy donors of blood components. 100 conditionally healthy donors examined at the Republican Center for Blood Transfusion took part in this study. Rhesus, Kell, and Kidd System red blood cell antigens were determined using monoclonal antibodies. The results indicate that in healthy donors, all 4 phenotypes of the Kell system antigens - K-k +, K-k-, K + k + and K + k- - are found. The most common phenotype was the phenotype - K-k + (92.9%). Kell phenotypes of healthy donors are arranged in the following sequence: K-k + K + k +> K + k-> K-k-. Our studies made it possible not only to understand the prevalence of major antigens of the AB0 system and Rhesus in all regions of the Republic of Uzbekistan, but also to consider the prevalence of phenotypes of antigens of the AB0 system, Rhesus and Kell in healthy donors.