Analysis of effect of iron deficiency anemia on HbA1c in diabetic patients in Pakistan

摘要

Introduction: Iron deficiency is one of the most prevalent forms of malnutrition. Globally, 50% of anemia isattributed to iron deficiency.Aims and objectives: The basic aim of the study is to analyse the effect of irondeficiency anemia on HbA1c in diabetic patients in Pakistan.Material and methods: This cross sectional studywas conducted in University College of MedicineandDentistry, University of Lahore during January 2019 toOctober 2019. This study include all diabetic patient who visited the OPD of the hospital. Socio-demographiccharacteristics were collected using structured questionnaires. An enrollment form containing past medical historypertaining to chronic diseases such as kidney disease, heart related problem, skin diseases, blood coagulationdisorders and other medical complaints were completed for every individual.Results: In 120 cases of this study,mean HbA1c value was found to be 6.87 ± 1.4%. The mean ferritin levels in male and female cases were 14.88 ±8.62 and 8.92 ± 5.72 ng/ml, respectively. Also, mean FPG concentration was 99.66 ± 14.73 mg/dl in total cases.Hemoglobin levels in male and female cases were 9.54 ± 1.4 and 9.37 ± 1.33 g/dl, respectively. The mean MCVwas 53.2 ± 8.16 fL and mean MCH was 17 ± 3.7 pg/cell for the all cases (both males and females).Conclusion: It isconcluded that Iron deficiency anemia elevates HbA1c levels in diabetic individuals with controlled plasma glucoselevels. The elevation is more in patients having plasma glucose levels between 100 to 126 mg/dl. Hence, beforealtering the treatment regimen for diabetes, iron deficiency anemia should be considered.