Remote Ischemic Preconditioning Correction in Adma-Like Gestosis Model.Vladimir Vladimirovich Gureev*, Sergei Alexandrovich Alehin, Mikhail Vladimirovich

摘要

ABSTRACT Simulation of ADMA-like gestosis model was performed by means of administering L-NAME to rats during the period from the 14th to the 20th day of pregnancy. The animals demonstrated increase of arterial pressure, proteinuria, placental microcirculation disorders, vascular control disorders and destructive changes in placenta having ischemic genesis. Reproduction of short ischemia-reperfusion episodes resulted in apparent correction of the morphofunctional disorders appearing during gesto.