Ten-year surveillance of antimicrobial resistance of Streptococcus pneumoniae in a south-west German teaching hospital

摘要

Pneumococcal resistance has shown a steady increase worldwide over recent decades.1 Penicillin-resistant pneumococci were first reported in Australia in 1967 and then became widespread during the 1980s and 1990s. Pneumococcal strains with resistance to erythromycin, tetracycline, and cotrimoxazole were also identified in the late 1960s and early 1970s.1 More recently, pneumococci resistant to extended-spectrum cephalosporins and fluoroquinolones have been reported in the United States, South Africa and Europe.