首页> 外文期刊>Journal of the International Aids Society >Peer counselling versus standard‐of‐care on reducing high‐risk behaviours among newly diagnosed HIV‐positive men who have sex with men in Beijing, China: a randomized intervention study
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Peer counselling versus standard‐of‐care on reducing high‐risk behaviours among newly diagnosed HIV‐positive men who have sex with men in Beijing, China: a randomized intervention study

机译:同伴咨询与照护标准在中国北京减少与男男性接触的新诊断艾滋病毒阳性男性中降低高危行为的研究:一项随机干预研究

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Abstract IntroductionReducing high-risk behaviours (i.e. multiple partnership, condomless anal/vaginal sex, alcohol use before sex, illicit drug use) after HIV diagnosis is critical for curtailing HIV transmission. We designed an intervention to explore peer- counselling in reducing high-risk behaviours among newly diagnosed HIV-positive Chinese men who have sex with men (MSM). MethodsWe randomized 367 newly diagnosed HIV-positive men to either standard-of-care (SOC; n?=?183) or peer-counselling intervention (n?=?184), and followed them for 12?months (visit at 0-, 3-, 6-, 9- and 12-month). SOC participants received counselling on high-risk behaviour reduction by clinic staff. Intervention participants received both SOC and peer counselling. A generalized estimating equation was used to compare pre-post diagnosis high-risk behaviour change; logistic regression was used to assess the likelihood of practicing high-risk behaviours between intervention and SOC participants. Both intent-to-treat and per-protocol (full-dosage) approaches were used for the analyses. ResultsFor pre- and post-diagnosis comparisons, multiple partnership fell from 50% to 16% ( p ConclusionsWe observed a 14 to 43% decrease in the prevalence of selected high-risk behaviours after HIV diagnosis. Peer counselling had a greater impact in reducing condomless anal sex with men, illicit drug use and condomless vaginal sex with women over time. Future studies with exclusive peer-counselling arm are necessary to test its efficacy and effectiveness among Chinese MSM.Clinical Trial Number: NCT01904877.
机译:摘要简介减少艾滋病毒诊断后,减少高风险行为(即多性伴侣,无避孕套的肛门/阴道性交,性交前饮酒,非法吸毒)对于减少艾滋病毒的传播至关重要。我们设计了一项干预措施,以探索同伴咨询,以减少新诊断出的与男性发生性关系的艾滋病毒呈阳性的中国男性中的高风险行为。方法我们将367名新诊断出的HIV阳性男性随机分为护理标准(SOC; n == 183)或同伴咨询干预(n == 184),并随访他们12个月(在0- ,3、6、9和12个月)。 SOC参与者接受了诊所工作人员有关减少高危行为的咨询。干预参与者都接受了SOC和同伴咨询。使用广义估计方程比较诊断后的高风险行为变化。 Logistic回归用于评估干预和SOC参与者之间实行高风险行为的可能性。意向性治疗和按方案(全剂量)方法均用于分析。结果对于诊断前和诊断后的比较,多重伙伴关系从50%下降到16%(p结论我们发现,在HIV诊断后,某些高危行为的患病率降低了14%至43%。同伴咨询对减少无避孕套的影响更大随着时间的流逝,男性与男性发生性行为,非法使用毒品以及女性与无避孕套发生阴道性行为,有必要进一步开展专门的同伴咨询臂研究,以检验其在中国MSM中的疗效和有效性。临床试验编号:NCT01904877。

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