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首页> 外文期刊>Journal of Neurosciences in Rural Practice >Spontaneous intracerebral hemorrhage: Clinical and computed tomography findings in predicting in-hospital mortality in Central Africans
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Spontaneous intracerebral hemorrhage: Clinical and computed tomography findings in predicting in-hospital mortality in Central Africans

机译:自发性脑出血:临床和计算机断层扫描发现可预测中部非洲人的院内死亡率

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Background and Purpose:Intracerebral hemorrhage (ICH) constitutes now 52% of all strokes. Despite of its deadly pattern, locally there is no clinical grading scale for ICH-related mortality prediction. The first objective of this study was to develop a risk stratification scale (Kinshasa ICH score) by assessing the strength of independent predictors and their association with in-hospital 30-day mortality. The second objective of the study was to create a specific local and African model for ICH prognosis.Materials and Methods:Age, sex, hypertension, type 2 diabetes mellitus (T2DM), smoking, alcohol intake, and neuroimaging data from CT scan (ICH volume, Midline shift) of patients admitted with primary ICH and follow-upped in 33 hospitals of Kinshasa, DR Congo, from 2005 to 2008, were analyzed using logistic regression models.Results:A total of 185 adults and known hypertensive patients (140 men and 45 women) were examined. 30-day mortality rate was 35% (n=65). ICH volume>25 mL (OR=8 95% CI: 3.1-20.2; P 7 mm, a consequence of ICH volume, was also a significant predictor of mortality. The Kinshasa ICH score was the sum of individual points assigned as follows: Presence of coma coded 2 (2 × 2 = 4), absence of coma coded 1 (1 × 2 = 2), ICH volume>25 mL coded 2 (2 × 2=4), ICH volume of ≤25 mL coded 1(1 × 2=2), left hemispheric site of ICH coded 2 (2 × 1=2), and right hemispheric site of hemorrhage coded 1(1 × 1 = 1). All patients with Kinshasa ICH score ≤7 survived and the patients with a score >7 died. In considering sex influence (Model 3), points were allowed as follows: Presence of coma (2 × 3 = 6), absence of coma (1 × 3 = 3), men (2 × 2 = 4), women (1 × 2 = 2), midline shift ≤7 mm (1 × 3 = 3), and midline shift >7 mm (2 × 3 = 6). Patients who died had the Kinshasa ICH score ≥16.Conclusion:In this study, the Kinshasa ICH score seems to be an accurate method for distinguishing those ICH patients who need continuous and special management. It needs to be validated among large African hypertensive populations with a high rate of 30-day in–hospital mortality.
机译:背景与目的:脑出血(ICH)现在占所有中风的52%。尽管有致命的模式,但在当地尚无用于ICH相关死亡率预测的临床分级量表。这项研究的第一个目标是通过评估独立预测因素的强度及其与医院30天死亡率的关系,制定风险分层量表(Kinshasa ICH评分)。该研究的第二个目标是建立一个针对ICH预后的特定本地和非洲模型。材料和方法:年龄,性别,高血压,2型糖尿病(T2DM),吸烟,饮酒和来自CT扫描(ICH)的神经影像学数据使用Logistic回归模型分析了2005年至2008年刚果金萨萨(Kingshasa)的33所医院中接受原发性ICH并进行随访的患者的数量,中线偏移)结果:总共185名成人和已知的高血压患者(140名男性)和45名女性)进行了检查。 30天死亡率为35%(n = 65)。 ICH体积> 25 mL(OR = 8 95%CI:3.1-0.2; P 7 mm,ICH体积的一个重要指标)也是死亡率的重要预测指标。KinshasaICH得分是按以下方式分配的各个分数的总和:昏迷编码2(2×2 = 4),无昏迷编码1(1×2 = 2),ICH体积> 25 mL编码2(2×2 = 4),ICH≤25mL编码1(1 ×2 = 2),ICH的左半球部位标记为2(2×1 = 2),出血的右半球部位标记为1(1×1 = 1)。所有Kinshasa ICH得分≤7的患者均存活,并且得分> 7死亡。考虑性别影响(模型3),允许得分如下:昏迷(2×3 = 6),不昏迷(1×3 = 3),男性(2×2 = 4) ),女性(1×2 = 2),中线移位≤7mm(1×3 = 3)和中线移位> 7 mm(2×3 = 6)。死亡患者的Kinshasa ICH评分≥16。 :在这项研究中,金沙萨ICH评分似乎是区分那些需要持续和特殊治疗的ICH患者的准确方法。需要在非洲30天住院死亡率很高的大型高血压人群中进行验证。

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