Lipoprotein (a): More than a bystander in the etiology of hypertension? A study on essential hypertensive patients not yet on treatment

摘要

Background: Hypertension (HTN) is a very common disorder with a substantial impact on public health because of its complications. Objectives: To study the association of serum lipoprotein(a) [Lp(a)] elevation with essential hypertension (eHTN). Patients and Methods: This study was conducted on a group of essential hypertensive patients. Laboratory exams consisting of serum creatinine and Lp(a) were measured. Results: Ninety five essential hypertensive patients were enrolled to the study. Serum LP (a) in patients was 46.5±20. In patients an inverse correlation between serum Lp(a) andcreatinine clearance was seen (r = -0.175 p Conclusions: Our data suggest that Lp(a) may be involved as a cofactor in essential hypertension, with a mechanism that remains to be elucidated