ASSESSMENT OF ANTIMICROBIAL POTENTIAL AND PHYTOCHEMICAL PROFILING OF ETHNOMEDICINAL PLANT BERGENIA CILIATA (HAW.) STERNB. IN WESTERN HIMALAYA

摘要

Western Himalaya is endowed with rich treasure of medicinal plant wealth. Bergenia ciliata is one of the important ethnomedicinal plants collected from Western Himalaya and used for dissolving kidney stones by the local inhabitants. In present work ethanolic rhizome extract of plant was evaluated for its medicinal potential by assessing its antimicrobial and phytochemical properties. In antimicrobial studies the ethanolic rhizome extract of the plant was used against standard and clinical isolates of selected pathogenic bacterial strains. Maximum inhibition zone (12±1.0mm) was observed against clinical isolate of S. typhimurium followed by clinical isolate of E. coli with an inhibition zone of 11.33±0.57mm. The MIC of B. ciliata rhizome extract ranged from 100 to 200μg/100μl against different pathogenic strains. The rhizome extract showed presence of reducing sugars, alkaloids, saponins, tannins, flavonoids and cardiac glycosides. Further, GC-MS analysis of rhizome extract confirmed the presence of phytochemicals viz., beta sitasterol, ethyl iso-allocholate, hexadecanoic acid, cetene, monolinolein TMS, berginin, gallic acid, linolool, β-caryophyllene, calcitriol, carotene, oleic acid and astaxanthin with significant ethnomedicinal importance.