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Evaluation of remineralizing potential of commercially available child formula dentifrices: An in vitro study

机译:评估市售儿童配方奶粉的再矿化潜力:一项体外研究

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Aim: The aim of this in vitro study is to evaluate the remineralizing potential of commercially available low fluoride child formula dentifrice on primary teeth. Materials and Methods: Total 30 primary teeth were placed in demineralizing solution for 96 hours to produce artificial carious lesions of approximately 100 μm depth, and then cut longitudinally into 30 sections of 100-150 μm thickness and randomly assigned to three groups. Sections were treated with dentifrices containing Colgate ® (anti tooth decay) 500 ppm NaF, Cheerio gel ® 458 ppm MFP and Vicco ® non-fluoridated dentifrice. Lesions were evaluated using polarized light microscopy. Results: Colgate ® (anti tooth decay) 500 ppm NaF sections exhibited a statistically significant decrease in lesion depth (P 0.05, paired t-test), whereas those in Cheerio gel ® 458 ppm MFP showed a decrease in lesion depth but was not statistically significant. Vicco ® non-fluoridated dentifrice showed increase in lesion depth. Statistics: A paired t-test is used to evaluate pre- and post-treatment lesion depth measurements, and Newman-Keuls multiple post hoc procedures was carried out to compare pair-wise difference of pre- and post-treatment lesion depth. Conclusion: The Colgate ® (anti tooth decay) 500 ppm NaF dentifrice and Cheerio gel ® 458 ppm MFP demonstrated remineralization of carious lesions by virtue of decrease in lesion depth, whereas Vicco ® non-fluoridated dentifrice showed increase in lesion depth.
机译:目的:这项体外研究的目的是评估市售低氟儿童配方洁齿剂在乳牙上的再矿化潜力。材料与方法:将总共30颗乳牙置于脱矿质溶液中96小时,以产生约100μm深度的人造龋齿病变,然后将其纵向切成30个100-150μm厚度的切片,并随机分为三组。用含有高露洁®(抗蛀牙)500 ppm NaF,Cheerio gel ® 458 ppm MFP和Vicco ®未氟化的洁牙剂处理切片洁牙剂。使用偏光显微镜评估病变。结果:高露洁®(抗蛀牙)500 ppm NaF切片显示病变深度有统计学意义的降低(P <0.05,配对t检验),而Cheerio gel ® sup> 458 ppm MFP显示病变深度减少,但无统计学意义。 Vicco ®非氟化洁牙剂的病灶深度增加。统计数据:配对t检验用于评估治疗前和治疗后病变深度的测量,并进行了Newman-Keuls多个事后程序以比较治疗前和治疗后病变深度的成对差异。结论:高露洁®(抗蛀牙)500 ppm NaF洁齿剂和Cheerio gel ® 458 ppm MFP由于病变深度减小而表现出龋病的再矿化,而Vicco ®非氟化洁牙剂的病变深度增加。

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