Evaluation of nitrous oxide inhalation sedation during inferior alveolar block administration in children aged 7-10 years: A randomized control trial

摘要

Background: Nitrous oxide-oxygen (N ₂ O-O ₂ ) is being used in combination with many drugs and this possess risk for leading to deep sedation or reflexes being compromised. Aim: The purpose of our study was to use N ₂ O-O ₂ alone, to evaluate its effectiveness for pain control during inferior alveolar nerve block administration in children. Design: This was a single-centered, simple randomized, double-blinded, placebo-controlled parallel-group study involving 40 children in the age group of 7-10 years divided into 2 groups: N ₂ O-O ₂ sedation and oxygen. Pain perception for local anesthesia was assessed using face, legs, activity, cry, consolability scale. Children's behavior was assessed using Frankl ratings, depth of sedation using Observer's Assessment of Alertness/Sedation scale. The vital signs and oxygen saturation were recorded. Results: There was a significantly lower pain reaction to local anesthetic administration in the N ₂ O-O ₂ group (P 2 O-O ₂ group during and after the procedure as compared to the O ₂ group (P Conclusion: Pain experienced by children receiving N ₂ O-O ₂ sedation was significantly lower. N ₂ O-O ₂ inhalation sedation produces adequate sedation with vital signs within normal limits and treatments successfully completed.