Changes and significance of procalcitonin, C-reactive protein, peripheral leukocyte count and prealbumin in patients with severe pneumonia

摘要

Objective: Analyze the expression and clinical significance of procalcitonin (PCT) C-reactive protein (CRP), white blood cell count (WBCC) and prealbumin (PAA) in severe pneumonia by grouping contrast study. Methods: A total of 161 cases of pneumonia were treated in a hospital from January 2017 to June 2017 as the research objects. According to the standard of severe pneumonia, 104 cases were divided into mild pneumonia group and 57 cases were divided into severe disease group. 60 healthy persons who came to our hospital for physical examination at the same time were taken as the control group.The general data of the three groups and the level of PCT, CRP, WBC, PA were compared and analyzed. Results: The age and male ratio of severe group were higher than those of control group and mild group; compared with control group, the expression of PCT, CRP, WBC in the two pneumonia group were significantly higher, while the expression of PA was significantly lower; however, the expression of PCT, CRP, WBC in severe group were significantly higher than that in mild group, while the expression of PA in severe group was significantly lower than that in mild group. PCT has higher sensitivity, specificity and accuracy among the four indexes and it has important diagnostic value. Conclusion: PCT has higher specificity, accuracy and sensitivity in the early diagnosis of severe pneumonia, and it can be used as an important index in the early diagnosis of severe pneumonia.But the combined detection of the three indexes of PCT, CRP and WBC is helpful for diagnosing severe pneumonia more accurately.