HRV changes before and after radiofrequency ablation in patients with different origin of right ventricular outflow tract ventricular premature contraction

摘要

Objective: To observe the HRV changes before and after the radiofrequency current catheterablationventricular premature beats originated from different site of right ventricular outflowtract. Methods: A total of 102 patients with frequent RVOT-VPC admitted to our hospital wereaccepted radiofrequency current catheter ablation (RF). According to the origin of RVOT-VPC,it was divided into 2 groups, one is from ventricular septum, and the other one is from freewall, and in each group, male and female are observed separately. Results: (1) HRV before RFablation: 1) rMSSD in the female patients with RVOT-VPC from free wall was significantlylower than those from septum; 2) frequency domain index (W, LF) were higher than normalrange, and in male patients, LF/HF1. (2) HRVafter RF ablation: 1) Significant changes were found in female patients with RVOT-VPC fromseptum, rMSSD, PNN50, HF and LF decreased; 2) In female patients with RVOT-VPC fromfree wall, rMSSD decreased; 3) In male patients, there were no significant HRV changes foundbefore and after RF ablation. (3) Heart rate changes: 1) In female patients with RVOT-VPCfrom septum, heart rate decreased significantly [(76.47±9.47) bpm vs (69.29±14.59) bpm]. 2)No significant changes were found in male patients. Conclusion: In patients with RVOT-PVCsympathetic and vagus excitability increased, and after catheter ablation, in female patientswith RVOT-PVC originated from septum, the HRV index relating to sympathetic and vagusexcitability significantly decreased.