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The cost of unresectable stage III or stage IV melanoma in Italy

机译:意大利不可切除的III期或IV期黑色素瘤的费用

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Background In recent decades, melanoma incidence has been increasing in European countries; in 2006, there were approximately 60,000 cases leading to 13,000 deaths. Within Europe there is some geographical variation in the incidence of melanoma, with the highest rates reported in Scandinavia (15 cases per 100,000 inhabitants per year) and the lowest in the Mediterranean countries (5 to 7 cases per 100,000 inhabitants per year). Methods The present article is based on the information collected in the MELODY study (MELanoma treatment patterns and Outcomes among patients with unresectable stage III or stage IV Disease: a retrospective longitudinal survey). In that study, the medical charts of patients were reviewed to document current treatment patterns and to analyse information on patients, disease characteristics and healthcare resource utilization related to the treatment of advanced melanoma regarding patients who presented with a diagnosis of malignant melanoma (stage I to IV) at participating sites between 01 July, 2005 and 30 June, 2006. Results Summarizing, though the length of the follow-up period varies among sample patients, an amount of the yearly cost per patient can be estimated, dividing the average per patient total cost (€ 5.040) by the average follow-up duration (17.5 months) and reporting to one year; on these grounds, unresectable stage III or stage IV melanoma in Italy would cost € 3,456 per patient per year.
机译:背景技术近几十年来,欧洲国家的黑色素瘤发病率一直在上升。 2006年,大约有60,000例病例导致13,000例死亡。在欧洲范围内,黑色素瘤的发病率存在地域差异,在斯堪的纳维亚半岛报告的发病率最高(每年每10万居民15例),而在地中海沿岸国家则最低(每年每100,000居民5至7例)。方法本文基于MELODY研究中收集的信息(不可切除的III期或IV期疾病患者的MELanoma治疗模式和结果:回顾性纵向调查)。在该研究中,对患者的病历进行了回顾,以记录当前的治疗模式,并分析与诊断为恶性黑色素瘤的患者有关的,与晚期黑色素瘤治疗相关的患者,疾病特征和医疗资源利用的信息(I期至IV)在2005年7月1日至2006年6月30日之间的参与地点。结果总结,尽管随访时间的长短因样本患者而异,但可以估算出每位患者的年度费用,除以每位患者的平均费用按照平均随访时间(17.5个月)并报告至一年的总费用(5.040欧元);基于这些理由,意大利不可切除的三期或四期黑色素瘤每人每年将花费3456欧元。

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