Local Field Isolates of Infectious Bursal Disease Virus (IBDV) in Bangladesh can Induce Higher Immune Response in Chickens than that of the Commercially Available IBDV Vaccines

摘要

The aim of the study is to detect the causes of vaccination failure in chickens against IBD in Bangladesh. One selected local field IBDV isolate, one commercially available live attenuated IBDV vaccine Bur-706 (RP) and one killed IBDV vaccine Gumboriffa (RP) were used in this study. A total of 100 chicks (Star brow) of 0,7,14,21 and 28 days age group (taking 20 in each group) were used for study the serologic response with a selected local field IBDV isolate. Similarly two other vaccines were vaccinated in each 100 chicks of similar age groups. After collection of sera weekly for upto six weeks from all groups of birds they were subjected to SNT, PHA test and AGPT against a specific IBDV antigen. Through this investigation it is found that the local field IBDV isolate demonstrate higher serologic response than that of commercially available live or killed IBDV vaccines. So, it may be concluded that the commercially available imported vaccines can not induce sufficient immune response to protect the chickens in Bangladesh. It may be due to degradation of the vaccine quality during transportation or in a new environmental condition or due to antigenic dissimilarities among the local field virus and the imported vaccines.