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首页> 外文期刊>Der chemica Sinica >Synthesis, characterization and antimicrobial activities of N-[{4-[2-{3,5-bis(4- methoxyphenyl)-4,5-dihydro-pyrazol-yl}-2-oxoethoxy]phenyl}methylene] substituted aniline
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Synthesis, characterization and antimicrobial activities of N-[{4-[2-{3,5-bis(4- methoxyphenyl)-4,5-dihydro-pyrazol-yl}-2-oxoethoxy]phenyl}methylene] substituted aniline

机译:N-[{{4- [2- {3,5-双(4-甲氧基苯基)-4,5-二氢-吡唑基-基} -2-氧乙氧基]苯基}亚甲基]取代的苯胺的合成,表征和抗菌活性

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Heterocyclic Compounds having a valuable place in a Heterocyclic Chemistry and Heterocyclic Compounds having a excellent properties such as drugs, dyes etc, This compounds are showing anti microbial , anti fungal , anti bacterial ,anti inflammatory ,anti diabetic ,anti hypertensive etc. properties. In present investigation, we have prepared N-[{4-[2-{3,5-bis(4-methoxyphenyl)-4,5-dihydro-pyrazol-1-yl}-2-oxoethoxy]phenyl} methyl ene] substituted aniline from chalcon of 1,3-bis(4- methoxyphenyl) prop-2-en-1-one and Schiff base of 2-(4-{[(substituted phenyl)imino]methyl} phenoxy)acetohydrazide. Compound having a excellent properties regarding as per as anti cancer and HIV as compare to this compound. Physical properties of pure crystallized substance N-[{4-[2-{3,5- bis(4-methoxyphenyl)-4,5-dihydro-pyrazol-1-yl}-oxoethoxy]phenyl}methylene] substituted aniline like M.P elementary analysis and spectral data of compound and such as IR and NMR will be evaluated and confirm the structure of compound. All the compounds were tested for their antibacterial and antifungal activities by broth dilution method.
机译:在杂环化学中具有重要地位的杂环化合物和具有优异性能的杂环化合物,例如药物,染料等,该化合物显示出抗微生物,抗真菌,抗细菌,抗炎,抗糖尿病,抗高血压等特性。在本研究中,我们制备了N-[{4- [2- {3,5-双(4-甲氧基苯基)-4,5-二氢吡唑-1-基} -2-氧乙氧基]苯基}亚甲基] 1,3-双(4-甲氧基苯基)丙-2-烯-1-酮的查尔酮取代的苯胺和2-(4-{[(取代的苯基)亚氨基]甲基}苯氧基)乙酰肼的席夫碱。与该化合物相比,该化合物在抗癌和HIV方面具有优异的性能。纯结晶物质N-[{4- [2- {3,5-双(4-甲氧基苯基)-4,5-二氢吡唑-1-基}-氧乙氧基]苯基}亚甲基]取代苯胺的物理性质,如MP将评估化合物的元素分析和光谱数据,例如IR和NMR,并确认化合物的结构。通过肉汤稀释法测试所有化合物的抗菌和抗真菌活性。

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