Staphylococcal scalded skin syndrome is a toxin-mediated, epidermolytic condition that uncommonly affects adults. A 51-year-old man receiving chemotherapy for leukemia presented with a large geographic erosion with superficial sloughing and multiple smaller lesions elsewhere. Biopsy revealed complete subcorneal splitting with multiple detached fragments of normal-appearing stratum corneum with fragments of attached acantholytic granular keratinocytes. Mild epidermal dysmaturation was also noted. Based on these findings, the patient was started on oral cephalexin, topical mupirocin, and topical clobetasol. His lesions improved significantly over the course of 1 week. ? 2014 S. Karger AG, Basel
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机译:葡萄球菌烫伤性皮肤综合症是一种毒素介导的表皮溶解性疾病,很少影响成年人。一名接受白血病化学疗法治疗的51岁男子,出现了较大的地理侵蚀,表层脱落,其他地方有多个较小的病变。活检显示,角膜下完全裂开,出现了多个正常出现的角质层分离的碎片,并附着了棘皮的角质化角质形成细胞碎片。还注意到轻度的表皮不成熟。基于这些发现,患者开始接受口服头孢氨苄,局部莫匹罗星和局部氯倍他索治疗。在1周的过程中,他的病变明显改善。 ? 2014巴塞尔S.Karger AG
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