Epidermal cyst (EC) of the skin is a very commoncondition. It is believed to originate from displacedepidermis in the dermis due to injury and other causes. Ithas been infrequently reported that squamous cell carcinoma (SCC) or squamous papilloma (SP) arises from EC [1–6]; only circa 20 such cases have been reported in theEnglish literature. In particular, only 1 case of SParising from an EC has been reported in the literature[5]. The author previously experienced an SCC arisingfrom an EC [4]. The author found 3 cases of SCCoriginating from EC and one case of SP developedwithin an EC in the author’s computer data base in thelast 15 years. Herein reported are these 4 cases.
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