Massive Necrotizing Pancreatitis in an Immunosuppressed Renal Transplant Recipient (Successful Therapy)

摘要

Severe pancreatitis may be associated with massive necrosis of the pancreas and/or retroperitonealadipose tissue. Toxicity results from the dead tissue and secondary infection. A 45 year old patient,while fully immunosuppressed, developed this complication following cadaveric renal transplantation.He survived continued immunosuppression, 16 operative debridements of the retroperitoneum, andmaintained a functioning renal transplant.In view of the previously reported high mortality rates from mild pancreatitis after transplantation,the current experience warrants further evaluation of the open method of treatment.