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Disparities in Medication Therapy in Patients with Heart Failure across the State of Hawai‘i

机译:夏威夷州心力衰竭患者药物治疗的差异

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The purpose of this study is to evaluate if heart failure patients in Hawai‘i are receiving recommended standard therapy of a select beta-blocker in combination with an ACE inhibitor (ACEI) or angiotensin receptor blocker (ARB), and to determine if a gap in quality of care exists between the different regions within the state. A retrospective claims-based analysis of all adult patients (age > 18 years of age) with CHF who were enrolled in a large health plan in Hawai‘i was performed (n = 24,149). Data collected included the presence of pharmaceutical claims for ACEI, ARBs and select β-blockers, region of residence, gender, and age. Multivariable logistic regression was used to examine whether there were regional differences in Hawai‘i related to medication usage, after adjustment for age and gender. Results showed that only 28.4 % of patients were placed on the recommended therapy of an ACEI or ARB and a select β-blocker with significant differences being found between different regions. Further research is needed to better understand factors affecting regional differences in prescribing patterns.
机译:这项研究的目的是评估夏威夷的心力衰竭患者是否正在接受推荐的标准β受体阻滞剂与ACE抑制剂(ACEI)或血管紧张素受体阻滞剂(ARB)组合的标准疗法,并确定是否存在差距在州内不同地区之间存在护理质量的提高。对参加夏威夷大健康计划的所有CHF成年患者(年龄大于18岁)进行回顾性基于索赔的分析(n = 24,149)。收集的数据包括ACEI,ARBs和部分β-受体阻滞剂的药物声称,居住地区,性别和年龄。在对年龄和性别进行调整之后,多变量logistic回归用于检验夏威夷人在药物使用方面是否存在地区差异。结果显示,只有28.4%的患者接受了推荐的ACEI或ARB和选择的β受体阻滞剂治疗,不同区域之间存在显着差异。需要进一步研究以更好地理解影响处方模式中区域差异的因素。

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