Tuberculin skin reactivity and T-lymphocyte subgroups in patients with chronic idiopathic urticaria

摘要

Background and Design: It has been demonstrated that the autologous serum skin test (ASST) has an important role in clinical test for detection of autoimmune-based urticaria. The aim of this study was to evaluate the ASST and cell immunity modifiers. MATERIALS-METHODS: We examined 68 patients and 37 control subjects, performed ASST and tuberculin skin reactivity (TST) and measured T-lymphocyte subsets. RESULTS: ASST was significantly positive in urticaria patients compared to control subjects. Thirty-two patients had positive TST reactivity. T-lymphocyte subsets were as follows: CD4: %41.3±3.4, CD8: %34±6.5, CD4/CD8: %1.2, CD3: %66±8.8. ASST was not related to the TST reactivity and T-lymphocyte subsets. CONCLUSION: These data provided that ASST does not seem to be associated with TST reactivity and T-lymphocyte subsets.