Effects on Sperms’ Quality of Selegiline in Aged Rats

摘要

Background:Selegiline is used to treat Parkinsonian patients. Other indications of its use have recently been discovered.Objective:Scouting special and beneficial side effects of selegiline treatment.Method:Two-year old male Wistar rats were daily treated with 0.25 mg/kg of selegiline s.c. (subcutaneous injection). The rats were sacrificed following a four-weeks’ treatment.Results:Mass of testes, number of sperms, progressive motility of sperms, and their viability definitely increased.Conclusion:Selegiline can successfully be used to stop/counterbalance certain symptoms of aging.