Enantioselective Potentiometric Membrane Eectrodes Based onα-,β-and γ-Cyclodextrins as Chiral Selectors for the Assay of S-Deprenyl

摘要

Enantioselective, potentiometric membrane electrodes (EPMEs) based on α,βand γ-cyclodextrins (CDs) aschiral selectors were proposed for the assay of S-deprenyl. The response characteristics proved that the proposed EPMEscould be reliably used in the assay of S-deprenyl. The best slope is exhibited by the EPME based on β-cyclodextrin. Thelimits of detection are very low: 10-9 mol L-1 magnitude order for β-cyclodextrin based EPME, and 10-11mol L-1 magnitude order for α, and γ-cyclodextrins based EPMEs. The surfaces of the electrodes are stable and easily renewable by polishing on alumina paper.