Subcritical Water Extraction (SWE) OF Eurycomanone and Eurycomanolfrom Eurycoma logifolia Jack Roots

摘要

As an alternative to tradition extraction method, the ability of subcritical water extraction(SWE) to extract bioactivecompounds, eurycomanone and eurycomanol from Eurycoma logifolia Jack was investigated. The operational parameters ofSWE, such as temperature, pressure and static extraction time were optimized using central composite design (CCD). Byapplying multiple regression analysis on the experiment data obtained, the result of the CCD was fitted with a second orderquadratic equation.. The results showed that the only significant variable which affects the extraction efficiency of bothcompounds is the extraction temperature. The optimal conditions of SWE were extraction temperature of 104°C, extractionpressure of 1700 psi, using one extraction cycle with a static extraction time of 14 min. The yield of these bioactive compoundsextracted using SWE was compared with that obtained by Soxhlet extraction using methanol as the extracting solvent