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Thoracic Endovascular Aortic Repair for Chronic DeBakey IIIb Aortic Dissection

机译:胸腔内血管主动脉修复术治疗慢性DeBakey IIIb主动脉夹层

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Patient Population and Data CollectionOperative TechniqueStatistical AnalysisResultsPatient Demographics and Operative CharacteristicsProcedural (30-Day or In-Hospital) and Follow-Up OutcomesAnatomic Features Associated With Thoracic Endovascular Aortic Repair OutcomesThoracic endovascular aortic repair (TEVAR) for chronic DeBakey IIIb dissection with associated descending aneurysm remains controversial. This study examines long-term results of TEVAR for this disorder including examination of anatomic features associated with TEVAR outcomes.MethodsBetween July 2005 and January 2013, 32 patients underwent TEVAR for chronic (>30 days) DeBakey IIIb dissection involving the descending thoracic aorta at a single institution and constituted the study cohort.ResultsThe mean interval from dissection to TEVAR was 32 ± 44 months (range, 1 to 146 months). There were no 30-day or in-hospital deaths, strokes, or paraplegia. During a 54-month median follow-up, there were no aortic-related deaths. Significant thoracic aneurysm sac regression (>1 cm) in the intervened segment was observed in 89%. Thoracic remodeling was not correlated with the number of visceral vessels arising from the true lumen or the number or size of residual distal fenestrations; failure of thoracic remodeling was associated with fenestrations distal to the endograft(s) in the descending thoracic aorta, most often stent graft-induced new entry tears. Complete resolution of the thoracic and abdominal false lumen after TEVAR was observed in 15.6% (n?= 5). All patients in this group had all visceral vessels arising from the true lumen and fewer than three residual distal fenestrations.ConclusionsThoracic endovascular aortic repair is effective for chronic DeBakey IIIb dissection with associated descending aneurysm, with excellent 30-day and long-term outcomes and significant aortic remodeling in the vast majority of patients. Thoracic remodeling does not appear dependent on distal anatomic characteristics of the true and false lumens, although care should be?taken to cover all thoracic fenestrations and avoid creation of stent graft-induced new entry tears to ensure clinical success. Complete aortic remodeling was observed only in the setting of all visceral vessels off the true lumen with fewer than three residual distal fenestrations, and this would appear the ideal anatomy for TEVAR in this scenario.CTSNet classification:26At least one third of patients treated medically for uncomplicated acute type B aortic dissection (TBAD) will?require surgery for aortic-related complications within 5 years of their dissection event. Most commonly, surgery is?required for aneurysmal dilation of the chronically dissected thoracic aorta, and once the aortic diameter exceeds 55 to 60 mm, the risk of rupture is estimated at 30% per?year [
机译:患者人群和数据收集手术技术统计分析结果患者人口统计学和手术特征手术(30天或住院)和随访结果与胸腔内血管主动脉修复相关的解剖特征胸腔内主动脉修复(TEVAR)用于慢性DeBakey IIIb切除伴相关性降支动脉瘤。该研究检查了该疾病的TEVAR长期结果,包括与TEVAR结果相关的解剖特征的检查方法。方法2005年7月至2013年1月之间,对32例患者进行了TEVAR长期(> 30天)DeBakey IIIb夹层手术,累及了胸主动脉降主动脉。结果从解剖到TEVAR的平均间隔为32±44个月(范围为1至146个月)。没有30天或医院内的死亡,中风或截瘫。在54个月的中位随访期间,没有主动脉相关的死亡。 89%的患者在介入节段胸腔动脉瘤囊明显消退(> 1 cm)。胸腔重塑与真正管腔产生的内脏血管数量或远端远端开窗的数量或大小无关。胸腔改建失败与降主动脉内膜远端开窗有关,最常见的是支架植入物引起的新进入眼泪。观察到TEVAR后胸腔和腹腔的完全消退率为15.6%(n = 5)。该组所有患者的所有内脏血管均来自真正的管腔,少于三个残留的远端窗孔。大多数患者的主动脉重塑。胸腔重塑似乎不依赖于真腔和假腔的远端解剖特征,尽管应注意覆盖所有胸腔开窗并避免产生支架植入物引起的新进入眼泪,以确保临床成功。仅在真正的管腔内的所有内脏血管均具有少于三个残余远端开窗的情况下,才能观察到主动脉完全重塑,在这种情况下,这似乎是TEVAR的理想解剖结构。CTSNet分类:26至少有三分之一的患者接受了药物治疗单纯性急性B型主动脉夹层(TBAD)在其夹层事件发生后的5年内将需要手术治疗主动脉相关并发症。最常见的是,需要进行手术以对慢性解剖的胸主动脉进行动脉瘤扩张,一旦主动脉直径超过55至60 mm,估计每年的破裂风险为30%[

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