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Statins And Coronary Artery Disease

机译:他汀类药物和冠状动脉疾病

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Statins have been proven to be clinically effective in both the prevention and treatment of coronary artery disease. Coronary artery disease is a common and serious condition due to an underlying pathology of atherosclerosis, which is caused mainly by increased levels of low-density lipoprotein that accumulate in the walls of the coronary arteries. The main treatment option for high cholesterol levels is a group of cholesterol-lowering drugs called statins. They act mainly on the liver enzymes responsible for cholesterol synthesis, reducing the production of cholesterol. This has been proven to be very effective in decreasing the morbidity and mortality associated with coronary artery disease, as evidenced in a number of clinical trials and studies using statins.
机译:他汀类药物已被证明在预防和治疗冠状动脉疾病方面均具有临床效果。由于潜在的动脉粥样硬化病理,冠状动脉疾病是一种常见且严重的疾病,这主要是由于堆积在冠状动脉壁中的低密度脂蛋白水平升高所致。高胆固醇水平的主要治疗选择是一组称为他汀类药物的降胆固醇药物。它们主要作用于负责胆固醇合成的肝酶,减少胆固醇的产生。如在许多使用他汀类药物的临床试验和研究中所证明的,这已被证明在降低与冠状动脉疾病相关的发病率和死亡率方面非常有效。

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