Association of FOXE1 Polyalanine Repeat Region with Papillary Thyroid Cancer

Martyn Bullock; Emma L. Duncan; Christine ONeill; Lyndal Tacon; Mark Sywak; Stan Sidhu; Leigh Delbridge; Diana Learoyd; Bruce G. Robinson; Marian Ludgate; Roderick J. Clifton-Bligh

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Association of FOXE1 Polyalanine Repeat Region with Papillary Thyroid Cancer

机译：FOXE1聚丙氨酸重复区与乳头状甲状腺癌的关联。

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Context:Polyalanine tract variations in transcription factors have been identified for a wide spectrum of developmental disorders. The thyroid transcription factor forkhead factor E1 (FOXE1) contains a polymorphic polyalanine tract with 12–22 alanines. Single-nucleotide polymorphisms (SNP) close to this locus are associated with papillary thyroid cancer (PTC), and a strong linkage disequilibrium block extends across this region.

机译：背景：已针对多种发育障碍确定了转录因子中的聚丙氨酸束变异。甲状腺转录因子叉头因子E1（FOXE1）包含具有12-22个丙氨酸的多态性聚丙氨酸。靠近该基因座的单核苷酸多态性（SNP）与甲状腺乳头状癌（PTC）有关，并且一个强连锁不平衡区遍布该区域。

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《The journal of clinical endocrinology and metabolism》 |2012年第9期|共6页
作者
Martyn Bullock; Emma L. Duncan; Christine ONeill; Lyndal Tacon; Mark Sywak; Stan Sidhu; Leigh Delbridge; Diana Learoyd; Bruce G. Robinson; Marian Ludgate; Roderick J. Clifton-Bligh;
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1. Association of FOXE1 Polyalanine Repeat Region with Papillary Thyroid Cancer [J] . Martyn Bullock, Emma L. Duncan, Christine ONeill, The journal of clinical endocrinology and metabolism . 2012,第9期

机译：FOXE1聚丙氨酸重复区与乳头状甲状腺癌的关联。
2. Genotype Analyses in the Japanese and Belarusian Populations Reveal Independent Effects of rs965513 and rs1867277 but Do Not Support the Role of FOXE1 Polyalanine Tract Length in Conferring Risk for Papillary Thyroid Carcinoma [J] . Nikitski Alyaksandr V., Rogounovitch Tatiana I., Bychkov Andrey, Thyroid: official journal of the American Thyroid Association . 2017,第2期

机译：日本和白俄罗斯人群的基因型分析揭示了RS965513和RS1867277的独立效果，但不支持Foxe1多丙胺道长度在赋予乳头状甲状腺癌风险的作用
3. Association of single nucleotide polymorphisms in FOXE1 and pre-MIR146A with papillary thyroid carcinoma [J] . Nadia Bagatian, Ohoud Subhi, Shireen Hussain, BMC Genomics . 2014,第2期

机译：FOXE1和MIR146A前体的单核苷酸多态性与甲状腺乳头状癌的关系
4. Exposure to Flame Retardant Chemicals in the Home and Increased Risk for Papillary Thyroid Cancer [C] . Kate Hoffman, Julie Ann Sosa, Amelia Lorenzo, Annual conference of the International Society of Exposure Science . 2016

机译：在家中接触阻燃化学品并增加乳头状甲状腺癌的风险
5. Polybrominated Diphenyl Ethers, Thyroid Hormones, and Risk of Papillary Thyroid Cancer [D] . Huang, Huang. 2021

机译：多溴二苯醚，甲状腺激素和乳头状甲状腺癌的风险
6. Association of single nucleotide polymorphisms in FOXE1 and pre-MIR146A with papillary thyroid carcinoma [O] . Nadia Bagatian, Ohoud Subhi, Shireen Hussain, 2014

机译：FOXE1和MIR146A之前的单核苷酸多态性与甲状腺乳头状癌的关系
7. Association of FOXE1 Polyalanine Repeat Region with Papillary Thyroid Cancer [O] . Bullock, Martyn, Duncan, Emma L., O'Neill, Christine, 2012

机译：FOXE1聚丙氨酸重复区与乳头状甲状腺癌的关联。

Association of FOXE1 Polyalanine Repeat Region with Papillary Thyroid Cancer

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