Adenoid cystic carcinoma of breast

摘要

Adenoid cystic carcinoma of the breast is a very rare neoplasm. It has a biological course of slow progression and absence of lymph node metastasis. In contrast to extra mammary adenoid cystic carcinoma, the prognosis of adenoid cystic carcinoma is excellent This unusual neoplasm of the breast has certain histo-pathological and biological characteristics that differentiates it from more common histologic types. Clinical experience has shown that this entity has a low propensity for local recurrence after excision. We present a case of a 55 year old female who presented to us a with a painless swelling in the upper outer quadrant of left breast .Fine needle aspiration revealed adenoid cystic carcinoma. The patient underwent quadrantectomy. Histopathological examination confirmed adenoid cystic carcinoma of the left breast. Postoperatively the patient received radiotherapy and chemotherapy. The patient is doing well . Case report A 55 year old postmenopausal woman presented with a 2 years history of palpable mass in the left breast. The lump was painless and there was no history of any discharge through the nipple. She had reached menopause 5 years back and had four children. She attained menarchy at the age of 14 years. Physical examination revealed a mass of 4 x 5 cms in the upper outer quadrant of left breast with no stain or nipple changes. There was no palpable axillary lymphadenopathy. Mammography revealed a well defined regular marginated, homogenous nodular density lesion located in upper outer quadrant of the left breast. FNAC of the lesion was advised that revealed features of adenoid cystic carcinoma of the breast(Fig. 1). Smear showed cylinders of hyaline stroma, surrounded by tumour cells. Tumour cells were monomorphic with scanty cytoplasm, hyperchromatic nuclei, course chromatin and indistinct nucleoli.