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Familial sarcoidosis in a jordanian family

机译:约旦家庭的家族结节病

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Abstract Sarcoidosis is an idiopathic granulomatous disease involving one or more multiple organ systems, characterised by the histologic finding of noncaseating epitheloid cell granulomas. This is the first report of familial sarcoidosis in Jordan. We report a mother and her son who Presented with bilateral hilar lymphadenopathy and lung infiltrates. Sarcoidosis is a rare disease in Jordan. We reported thirty-three cases of sarcoidosis(1). Although the familial tendency is reported in many studies(2), this was not the case in our study. Though the etiology is unknown; both Prevalence of sarcoidosis in different ethnic groups and familial occurrence of the disease strongly suggest the hypothesis of a possible genetic predisposition(3).
机译:摘要结节病是一种涉及一个或多个多器官系统的特发性肉芽肿性疾病,其特征为非干酪样上皮细胞肉芽肿的组织学发现。这是约旦家族结节病的首次报道。我们报道了一位母亲和她的儿子出现双侧肺门淋巴结肿大和肺浸润。结节病是约旦罕见的疾病。我们报告了33例结节病(1)。尽管在许多研究中都报道了家族倾向(2),但在我们的研究中并非如此。虽然病因不明;在不同种族的结节病患病率和家族性疾病的发生都强烈提示可能存在遗传易感性的假设(3)

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