This study investigated the relationship between depression, somatization, anxiety, personality, and laryngopharyngeal reflux (LPR). We prospectively analyzed 231 patients with symptoms with LPR using the laryngopharyngeal reflux symptom index and the reflux finding score. Seventy nine (34.2%) patients were diagnosed with LPR. A significant correlation was detected between the presence of LPR and total scores on the Patient Health Questionnaire-9 (5.6±5.3 vs. 4.0±4.6, p=0.017) and the 7-item Generalized Anxiety Disorder Scale (4.3±4.9 vs. 3.0±4.5, p=0.041). LPR was significantly more frequent in those with depression than in those without (45.6% vs. 27.0%, p=0.004). A multivariate analysis confirmed a significant association between the presence of LPR and depression (odds ratio, 1.068; 95% confidence interval, 1.011–1.128; p=0.019). Our preliminary results suggest that patients with LPR may need to be carefully evaluated for depression.
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机译：这项研究调查了抑郁症，躯体化，焦虑，人格和喉咽反流（LPR）之间的关系。我们使用喉咽反流症状指数和反流发现评分对231例LPR症状患者进行前瞻性分析。七十九名（34.2％）患者被诊断出患有LPR。在LPR的存在与患者健康调查问卷9（5.6±5.3 vs. 4.0±4.6，p = 0.017）和7项广义焦虑症量表（4.3±4.9 vs. 3.0）的总分之间发现了显着相关性。 ±4.5，p = 0.041）。与没有抑郁症的人相比，LPR在抑郁症患者中的发生率明显更高（45.6％vs. 27.0％，p = 0.004）。多元分析证实LPR的存在与抑郁之间存在显着相关性（优势比1.068; 95％置信区间1.011-1.128; p = 0.019）。我们的初步结果表明，可能需要对LPR患者进行抑郁评估。
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