Peritoneal dialysis?related peritonitis in the years 2005–2007 among patients of the Peritoneal Dialysis Clinic f the Department of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University in Szczecin

摘要

Introduction. Peritoneal dialysis?related peritonitis (PDRP) is the most common complication of dialysis in patients undergoing continuous ambulatory peritoneal dialysis. Objectives. The study analyzes incidence of PDRP, pathogens responsible for the disease and response to treatment in patients at the Peritoneal Dialysis Clinic of the Department of Nephrology, Transplantology and Internal Medicine of Pomeranian Medical University and the Independent Public University Hospital N° 2 in Szczecin in the years 2005–2007. Patients and methods. Within 36 months, 20 peritonitis incidents have been diagnosed in 18 subjects of 89 patients undergoing peritoneal dialysis. Results. The incidence of PDRP was 1 episode/32 patient?months with 45% of PDRP episodes caused by Gram?positive bacteria, 40% by Gram?negative bacteria, and 5% by fungi. Staphylococcus aureus was the most common pathogen among Gram?positive bacteria and so were equally Klebsiella oxytoca and Enterobacter cloacae among Gram?negative bacteria. A satisfactory percentage of successful standard therapy (80%) was achieved; in 20% of PDRP cases removal of the Tenckhoff catheter was necessary. Conclusions. A higher proportion of PDRP caused by Gram?negative bacteria has been observed as compared to the data from other centers. There was high susceptibility of the isolated strains to third?generation cephalosporins and chinolones. Low incidence of PDRP in the center and bacteriological profile of strains causing the disease confirm high qualifications and training quality of the patients and the correct insertion of dialysis catheters.