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Herbal extracts in oral health care - A review of the current scenario and its future needs

机译:口腔保健中的草药提取物-当前情况及其未来需求的回顾

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Background:Oral diseases are among the major public health problems and the commonest of chronic diseases that affect mankind. The application of natural products for the control of oral diseases is considered as an interesting alternative to synthetic antimicrobials due to their lower negative impact, and for the effort to overcome primary or secondary resistance to the drug during therapy.Objective:To review the current evidence on the antimicrobial efficacy of 10 plant extracts on dental caries and plaque microorganisms.Materials and Methods:A comprehensive literature search was made by one of the authors for 2 months in PubMed, PubMed Central, MEDLINE, LILACS/BBO, Cochrane database of systematic reviews, SCIENCE DIRECT, and Google scholar databases. The results from the relevant published literatures are discussed.Summary and Conclusion:The extracts of Azadirachta Indica, Ocimum sanctum, Murraya koenigii L., Acacia nilotica, Eucalyptus camaldulensis, Hibiscus sabdariffa, Mangifera indica, Psidium guajava, Rosa indica, and Aloe barbadensis Miller have all been found to inhibit certain dental caries and periodontal pathogens. The current evidence is on individual plant extracts against bacteria involved in either caries or periodontitis. “Herbal shotgun” or “synergistic multitarget effects” are the terms used for the strategy of combining different extracts. The research assessing the antimicrobial efficacy of a combination of these plant extracts against dental caries and periodontal pathogens is the need of the hour, and such research will aid in the development of a novel, innovative method that can simultaneously inhibit two of the most common dental diseases of mankind, besides slowing the development of drug resistance.
机译:背景:口腔疾病是主要的公共卫生问题之一,也是影响人类的最常见的慢性疾病。天然产物用于控制口腔疾病被认为是合成抗菌剂的一种有趣替代方法,因为它们的负面影响较小,并且在治疗过程中努力克服对药物的原发性或继发性耐药性。目的:审查当前证据材料和方法:作者之一在PubMed,PubMed Central,MEDLINE,LILACS / BBO,Cochrane系统评价数据库中进行了为期2个月的全面文献检索,以研究10种植物提取物对龋齿和牙菌斑微生物的抗菌功效。 ,SCIENCE DIRECT和Google Scholar数据库。总结和结论:印度印za,圣殿,乌拉木,欧洲相思,桉树,樟木,芙蓉,印度Man,番石榴,番石榴,巴西Rosa和芦荟的提取物。已经发现所有这些都抑制某些龋齿和牙周病原体。目前的证据是针对植物提取物的抗龋齿或牙周炎的细菌。 “草药散弹枪”或“协同多目标效应”是用于组合不同提取物的策略的术语。评估这些植物提取物的组合对龋齿和牙周病原体的抗微生物功效的研究是一个小时的需要,而这种研究将有助于开发一种新颖,创新的方法,该方法可以同时抑制两种最常见的牙齿人类疾病,除了减缓耐药性的发展。

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