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A Comparison of Kyphoplasty, Vertebroplasty, or Non-Surgical Treatment of Traumatic/Atraumatic Osteoporotic Vertebral Compression Fractures: A Short Review

机译:创伤性/无创伤性骨质疏松性椎体压缩骨折的后凸成形术,椎体成形术或非手术治疗的比较:简短回顾

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Background: Although the majority of patients with traumatic/atraumatic osteoporotic vertebral compression fractures (OVCFs) may be managed with non-surgical treatment (NST), a subset (e.g. 40%) with significant pain, loss of vertebral height, and other factors may warrant percutaneous vertebroplasty (V), or percutaneous kyphoplasty (K). Methods: We compared the impact of these three treatment modalities, V, K, or NST, for managing OVCFs. Results: In several studies, both V and K resulted in comparable improvement in pain relief, postoperative kyphotic angles, increased anterior vertebral heights, and frequency of leakage of bone cement. One study evaluating 16 RCT’s (Randomized Controlled Studies), however, observed K significantly; “decreased the kyphotic wedge angle, increased the postoperative vertebral body height, and decreased the risk of cement leakage vs. V”. Further, in some series, both V and K resulted in higher quality of life scores and better pain relief vs. NST, while other studies showed V was superior to K. Further, although the risk of adjacent level fractures (ALF) following V, K, and NST were comparable in most studies, one clearly demonstrated NST had the lowest incidence of ALF. Despite all these findings, most studies concluded outcomes were comparable for all 3 groups. Conclusions: Although most OVCFs are still managed with non-surgical treatment (NST), a subset (e.g. about 40%) may warrant V or K. Although both V and K have been shown to result in significantly better pain relief, higher quality of life scores, increased postoperative vertebral body height compared with NST, outcomes for all 3 groups remained the same.
机译:背景:尽管大多数有创伤/无创伤性骨质疏松性椎体压缩性骨折(OVCF)的患者可以通过非手术治疗(NST)进行治疗,但仍有一部分(例如40%)伴有严重疼痛,椎高下降和其他因素需要经皮椎体成形术(V)或经皮椎体后凸成形术(K)。方法:我们比较了这三种治疗方式(V,K或NST)对管理OVCF的影响。结果:在几项研究中,V和K均在疼痛缓解,术后后凸角,前椎高增加和骨水泥渗漏频率方面产生了相当的改善。然而,一项评估16个RCT(随机对照研究)的研究显着观察到了K。 “降低后凸楔形角,增加术后椎体高度,并降低水泥渗漏相对于V的风险”。此外,在某些系列中,与NST相比,V和K均能获得更高的生活质量评分和更好的止痛效果,而其他研究则表明V优于K。此外,尽管V导致邻近水平骨折(ALF)的风险, K和NST在大多数研究中具有可比性,其中一项清楚地表明NST的ALF发生率最低。尽管有所有这些发现,但大多数研究得出的结论对于所有3组都是可比较的。结论:尽管大多数OVCF仍采用非手术治疗(NST),但仍有一部分(例如约40%)可能需要V或K。尽管已证明V和K均能显着改善疼痛,但其质量较高。生命评分,术后椎体高度较NST升高,所有3组的结果均相同。

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