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Evaluation of Oral and Parenteral Iron Treatment Preparations in Pregnant Women with Iron Deficiency Anemia

机译:缺铁性贫血孕妇口服和胃肠外铁剂的评价

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Objectives: to evaluate efficacy and safety of oral and parenteral iron preparations in pregnant women with iron deficiency anemia. Subjects and Methods: this clinical trial completed Between August 2015 and December 2016, at Department of Obstetrics and Gynecology in Quesna Emergency Hospital in the wake of acquiring an endorsement of its institutional board audit. The review members are 121 pregnant ladies (mean age 25.5 years; extend 20 to 40 years), (mean GA 24 weeks; rang 16 to 28 weeks) who go to the obstetric outpatient facility for antenatal care with the conclusion of iron inadequacy Anemia. Results : From the results it can be concluded that parenteral iron more powerful than oral iron and the term of treatment was less in parenteral group. In our study oral iron preparation demonstrates a similar outcome toward the finish of the review however iron poly maltose complex shows more GIT up sets more than ferrous sulfate. Parenteral iron poly maltose complex shows huge augmentation in Hb, serum iron and serum ferritin yet this outcome switched toward the finish of the study and iron sucrose turn out to be more powerful. From the results it can be concluded that parenteral iron more powerful than oral iron and the term of treatment was less in parenteral group. Conclusion : From the results it can be concluded that parenteral iron treatment was better endured with higher increment in mean hemoglobin when contrasted with oral iron treatment. There were no genuine reactions with parentraliorn therapy. Parentraliorn therapy is a good substitute to oral iron therapy in moderate to severe anemia.
机译:目的:评估口服和肠胃外铁剂对缺铁性贫血孕妇的疗效和安全性。受试者与方法:该临床试验于2015年8月至2016年12月在Quesna急诊医院的妇产科完成,并获得了其机构董事会审核的认可。审查成员为121名孕妇(平均年龄25.5岁;年龄延长20至40岁),(平均GA 24周;范围16至28周),他们去了产科门诊接受产前检查,发现铁缺乏症。结果:从结果可以得出,肠胃外铁剂比口服铁剂更有效,并且肠胃外治疗期限较少。在我们的研究中,口服铁制剂对本研究的结局显示出相似的结果,但是聚麦芽糖铁复合物比硫酸亚铁显示更多的GIT。肠胃外铁多聚麦芽糖复合物显示血红蛋白,血清铁和血清铁蛋白大量增加,但结果转为研究结束,蔗糖铁证明其功能更强大。从结果可以断定,肠胃外铁剂比口服铁剂更有效,并且肠胃外治疗期限较少。结论:从结果可以得出,与口服铁剂治疗相比,肠胃外铁剂治疗效果更好,平均血红蛋白增量更高。胃肠外用药治疗没有真正的反应。在中度至重度贫血中,肠胃外疗法可替代口服铁疗法。

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