Effects of human chorionic gonadotropin combined with clomiphene on Serum E'2, FSH, LH and PRL levels in patients with polycystic ovarian syndrome

摘要

Objective: Effects of human chorionic gonadotropin combined with clomiphene on serum E"2, FSH, LH and PRL levels in patients with polycystic ovarian syndrome were analyzed. Methods: 90 patients with polycystic ovarian syndrome treated from January 2015 to March 2016 were randomly and evenly divided into control group and observation group. Patients in the control group were only treated with clomiphene. On the basis of the treatment in control group, human chorionic gonadotropin was added in the treatment of observation group. The changes of E"2, FSH, LH, PRL levels were compared between two groups before and after the treatment. Clinical curative effects of patients in the two groups was evaluated. Adverse reactions during treatment in two groups were observed and recorded. The incidence of adverse reactions was calculated. Results: Serum E"2, FSH, LH and PRL levels in the two groups decreased significantly after treatment compared with that before treatment. The difference is statistical significant (P 0.05). Conclusion: Combined use of human chorionic gonadotropin can significantly reduce serum E"2, FSH, LH and PRL levels, improve clinical curative effects and reduce the incidence of adverse reactions. Human chorionic gonadotropin has high application value on the treatment of polycystic ovary syndrome.