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Advancement in Molecular Genetics to understand the molecular reproduction of Livestock – follicular development

机译:分子遗传学的进步,以了解家畜的分子繁殖-卵泡发育

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Follicular development in the mammalian ovary is a complex process which is potentially regulated by an orchestrated action of the pituitary gonadotropins, e.g., follicle stimulating hormone (FSH) and luteinizing hormone (LH), and local ovarian factors, such as peptide growth factors and steroids. Along with hormonal activation it is necessary to have tight coordination of expression of genes during follicular development. This review highlights the structure and function of ovary, follicle and follicular development. This review also confirms the temporal and spatial expression of the specific genes and miRNAs and their involvement in different modulators, the synthesis of active factors, their interactions, and the dynamics of their receptors on the follicular cell surface may be the ultimate determinants of cellular events which are crucial to coordinated growth and differentiation of follicular cells leading to folliculogenesis and ovulation. DOI: http://dx.doi.org/10.3329/ralf.v1i1.22355 Res. Agric., Livest. Fish. 1 (1): 47-60, Dec 2014.
机译:哺乳动物卵巢中的卵泡发育是一个复杂的过程,可能受垂体促性腺激素(例如卵泡刺激激素(FSH)和黄体生成激素(LH))以及局部卵巢因子(例如肽生长因子和类固醇)的协调作用调节。随着激素的激活,在卵泡发育过程中必须紧密协调基因的表达。这篇综述突出了卵巢,卵泡和卵泡发育的结构和功能。这篇综述还证实了特定基因和miRNA的时空表达及其在不同调节剂中的参与,活性因子的合成,它们之间的相互作用以及它们在滤泡细胞表面上的受体动力学可能是细胞事件的最终决定因素。这对于导致卵泡发生和排卵的卵泡细胞协调生长和分化至关重要。 DOI:http://dx.doi.org/10.3329/ralf.v1i1.22355 Res。 Agric。,Livest。鱼。 1(1):47-60,2014年12月。

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