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Salt Effect on the Antioxidant Activity of Red Microalgal Sulfated Polysaccharides in Soy-Bean Formula

机译:盐对大豆配方中红色微藻硫酸盐多糖抗氧化活性的影响

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Sulfated polysaccharides produced by microalgae, which are known to exhibit various biological activities, may potentially serve as natural antioxidant sources. To date, only a few studies have examined the antioxidant bioactivity of red microalgal polysaccharides. In this research, the effect of different salts on the antioxidant activities of two red microalgal sulfated polysaccharides derived from Porphyridium sp. and Porphyridium aerugineum were studied in a soy bean-based infant milk formula. Salt composition and concentration were both shown to affect the polysaccharides’ antioxidant activity. It can be postulated that the salt ions intefer with the polysaccharide chains’ interactions and alter their structure, leading to a new three-dimensional structure that better exposes antiooxidant sites in comparison to the polysaccharide without salt supplement. Among the cations that were studied, Ca2+ had the strongest enhancement effect on antioxidant activities of both polysaccharides. Understanding the effect of salts on polysaccharides’ stucture, in addition to furthering knowledge on polysaccharide bioactivities, may also shed light on the position of the antioxidant active sites.
机译:由微藻产生的硫酸化多糖,已知具有各种生物活性,可能潜在地用作天然抗氧化剂。迄今为止,只有很少的研究检查了红色微藻多糖的抗氧化生物活性。在这项研究中,不同的盐对两种来源于紫菜属的红色微藻硫酸盐化多糖的抗氧化活性的影响。以大豆为基础的婴儿配方奶粉中研究了铜绿和铜绿卟啉。盐的成分和浓度都显示出影响多糖的抗氧化活性。可以推测,盐离子与多糖链的相互作用相互干扰并改变其结构,从而导致一种新的三维结构,与不添加盐的多糖相比,该结构更好地暴露了抗氧化位点。在所研究的阳离子中,Ca 2 + 对两种多糖的抗氧化活性均具有最强的增强作用。除了进一步了解多糖的生物活性外,了解盐对多糖结构的影响,还可以阐明抗氧化剂活性部位的位置。

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