Comparison of homogeneous and heterogeneous Ga(III) catalysis in the cycloisomerization of 1,6-enynes

摘要

We describe a study of the gallium(III)-catalyzed 1,6-enynes cycloisomerization reaction in both homogeneous and heterogeneous conditions. With GaBr3 in homogeneous conditions, some particularities were observed in terms of selectivity compared to reported GaCl3-catalyzed reactions. The transfer of the reaction in heterogeneous conditions was realized by supporting Ga(III) salts onto montmorillonite. Both systems were compared based on reaction times, conversion, and selectivity and showed complementary activities.