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Transdermal fluid loss in severely burned patients

机译:严重烧伤患者的透皮液体流失

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Introduction: The skin protects against fluid and electrolyte loss. Burn injury does affect skin integrity and protection against fluid loss is lost. Thus, a systemic dehydration can be provoked by underestimation of fluid loss through burn wounds. Purpose: We wanted to quantify transdermal fluid loss in burn wounds. Method: Retrospective study. 40 patients admitted to a specialized burn unit were analyzed and separated in two groups without (Group A) or with (Group B) hypernatremia. Means of daily infusion-diuresis-ratio (IDR) and the relationship to totally burned surface area (TBSA) were analyzed. Results: In Group A 25 patients with a mean age of 47±18 years, a mean TBSA of 23±11%, and a mean abbreviated burned severity index (ABSI) score of 6.9±2.1 were summarized. In Group B 15 patients with a mean age of 47±22 years, a mean TBSA of 30±13%, and a mean ABSI score of 8.1±1.7 were included. Statistical analysis of the period from day 3 to day 6 showed a significant higher daily IDR-amount in Group A (Group A vs. Group B: 786±1029 ml vs. –181±1021 ml; p Conclusions: There is a systemic relevant transdermal fluid loss in burn wounds after severe burn injury. Serum sodium concentration can be used to calculate need of fluid resuscitation for fluid maintenance. There is a need of an established fluid removal strategy to avoid water and electrolyte imbalances.
机译:简介:皮肤可防止水分和电解质流失。烧伤确实会影响皮肤的完整性,并且失去对液体流失的保护。因此,由于低估了烧伤创面造成的液体流失,可能引起全身性脱水。目的:我们希望量化烧伤创面的透皮液体流失。方法:回顾性研究。分析了40名进入专门烧伤病房的患者,并将其分为两组,分别为(A组)或(B组)高钠血症。分析了每日输注-利尿率(IDR)的方法以及与总燃烧表面积(TBSA)的关系。结果:在A组25例患者中,平均年龄为47±18岁,平均TBSA为23±11%,平均缩写烧伤严重度指数(ABSI)为6.9±2.1。在B组中,平均年龄为47±22岁的15例患者中,平均TBSA为30±13%,平均ABSI评分为8.1±1.7。从第3天到第6天的统计分析显示,A组的每日IDR量显着较高(A组与B组:786±1029 ml对–181±1021 ml; p结论:存在系统相关性严重烧伤后烧伤创面的透皮液体流失,可以使用血清钠浓度来计算维持液体的液体复苏的需要,需要一种既定的液体清除策略,以避免水和电解质的失衡。

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