Comparative Genomics of the Mucoid and Nonmucoid Strains of Streptococcus pyogenes, Isolated from the Same Patient with Streptococcal Meningitis

Haruno Yoshida; Yasuhito Ishigaki; Asako Takizawa; Kunihiko Moro; Yuki Kishi; Takashi Takahashi; Hidenori Matsui

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Comparative Genomics of the Mucoid and Nonmucoid Strains of Streptococcus pyogenes, Isolated from the Same Patient with Streptococcal Meningitis

机译：化脓性链球菌的粘液和非粘液菌株的比较基因组学，从同一患者的链球菌性脑膜炎分离

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Mucoid (MTB313) and nonmucoid (MTB314) strains of group A streptococcus emm type 1 were simultaneously isolated from a single patient suffering from streptococcal meningitis. Whole-genome sequencing revealed that MTB313 carried a nucleotide substitution within rocA, which generated an amber termination codon.

机译：同时从一名患有链球菌性脑膜炎的患者中分离出1型A型链球菌的粘液（MTB313）和非粘液（MTB314）菌株。全基因组测序表明，MTB313在rocA内进行核苷酸取代，从而产生琥珀色终止密码子。

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《Genome Announcements》 |2015年第2期|共2页
作者
Haruno Yoshida; Yasuhito Ishigaki; Asako Takizawa; Kunihiko Moro; Yuki Kishi; Takashi Takahashi; Hidenori Matsui;
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中图分类基因工程（遗传工程）;
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专利

1. Increased expression of the ska gene in emm49-genotyped Streptococcus pyogenes strains isolated from patients with severe invasive streptococcal infections. [J] . Ikebe T, Endoh M, Watanabe H Japanese journal of infectious diseases . 2005,第5期

机译：从严重侵袭性链球菌感染患者中分离出的emm49基因型化脓性链球菌菌株中ska基因的表达增加。
2. Drug susceptibility and analysis using pulsed-field gel electrophoresis of Streptococcus pyogenes strains isolated from the patients with streptococcal toxic shock syndrome (STSS) in Japan [J] . Okuno R, Endoh M, Shimojima Y, 感染症学雑誌 . 2005,第4期

机译：从日本链球菌毒性休克综合征（STSS）患者中分离出的化脓性链球菌菌株的药敏性和脉冲场凝胶电泳分析
3. Drug susceptibility and analysis using pulsed-field gel electrophoresis of Streptococcus pyogenes strains isolated from the patients with streptococcal toxic shock syndrome (STSS) in Japan [J] . Okuno R, Endoh M, Shimojima Y, 感染症学雑誌 . 2005,第4期

机译：利用脉冲型凝胶电泳的药物敏感性和分析，从患有中日患者中分离出患者的链球菌菌株菌株（STSS）
4. Increased expression of ska gene in emm49-genotyped strains of Streptococcus pyogenes isolated from patients of severe invasive group A streptococcus infections [C] . Tadayoshi Ikebe, Haruo Watanab Lancefield International Symposium on Streptococci and Streptococcal Diseases . 2006

机译：从严重侵入性群体感染患者中分离的eMM49基因分型菌株中SKA基因表达的增加
5. Integrating proteomics, genomics, and bioinformatics tools to define unique features of the M1T1 clone of Streptococcus pyogenes. [D] . Aziz, Ramy Karam. 2005

机译：整合蛋白质组学，基因组学和生物信息学工具，以定义化脓性链球菌M1T1克隆的独特功能。
6. Comparative Genomics of the Mucoid and Nonmucoid Strains of Streptococcus pyogenes Isolated from the Same Patient with Streptococcal Meningitis [O] . Haruno Yoshida, Yasuhito Ishigaki, Asako Takizawa, 2015

机译：化脓性链球菌的粘液和非粘液菌株的比较基因组学从同一患者的链球菌性脑膜炎分离
7. Comparative Genomics of the Mucoid and Nonmucoid Strains of Streptococcus pyogenes, Isolated from the Same Patient with Streptococcal Meningitis [O] . Haruno Yoshida, Yasuhito Ishigaki, Asako Takizawa, 2015

机译：粘液性链球菌粘膜球菌和非态菌株的比较基因组学，与链球菌性脑膜炎的同一患者分离出来

Comparative Genomics of the Mucoid and Nonmucoid Strains of Streptococcus pyogenes, Isolated from the Same Patient with Streptococcal Meningitis

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