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首页> 外文期刊>European spine journal >Establishment of parameters for congenital stenosis of the cervical spine: an anatomic descriptive analysis of 1066 cadaveric specimens
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Establishment of parameters for congenital stenosis of the cervical spine: an anatomic descriptive analysis of 1066 cadaveric specimens

机译:先天性颈椎狭窄参数的建立:1066个尸体标本的解剖描述分析

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PurposeCongenital cervical stenosis (CCS) occurs when the bony anatomy of the cervical canal is smaller than expected in the general population predisposing an individual to symptomatic neural compression. No studies have defined CCS based on the normal population. The diagnosis is currently made based on clinical impression from radiographic studies. The aim of this study is to establish parameters that are associated with CCS, based on anatomic measurements on a large sample of skeletal specimens.MethodsFrom the Hamann-Todd collection at the Cleveland Museum of Natural History, 1,066 skeletal specimens were selected. Digital calipers were used to measure the sagittal canal diameter (SCD), interpedicular distance (IPD), and pedicle length. Canal area at each level was calculated using a geometric formula. A standard distribution was created and values that were 2 SD below mean were considered as congenitally stenotic. An analysis of deviance was performed to identify parameters that were associated with CCS. Regression analysis was used to determine odds ratios (OR) for CCS using these parameters.ResultsCCS was defined at each level as: C3/4?=?1.82?cm2, C4/5?=?1.80?cm2, C5/6?=?1.84?cm2, C6/7?=?1.89?cm2, C7/T1?=?1.88?cm2. Values of SCD??13?mm and IPD??22.5?mm were associated with CCS and yielded sensitivities and specificities of 88–100?% at each level. Logistic regression demonstrated a significant association between these parameters and presence of CCS with OR??18 at each level.ConclusionsBased on our study of a large population of adult skeletal specimens, we have defined CCS at each level. Values of SCD??13?mm and IPD??23?mm are strongly associated with the presence of CCS at all levels...
机译:目的先天性颈椎狭窄(CCS)发生在子宫颈管的骨解剖结构比一般人群中预期的要小时,这使个体容易出现症状性神经压迫。没有研究根据正常人群定义CCS。目前基于放射学研究的临床印象做出诊断。这项研究的目的是基于对大量骨骼标本的解剖测量结果,建立与CCS相关的参数。方法从克利夫兰自然历史博物馆的Hamann-Todd馆藏中,选择1,066个骨骼标本。使用数字卡尺测量矢状管直径(SCD),椎弓根距离(IPD)和椎弓根长度。使用几何公式计算每个级别的运河面积。创建了标准分布,将低于平均值2 SD的值视为先天性狭窄。进行偏差分析以识别与CCS相关的参数。使用这些参数,通过回归分析确定CCS的优势比(OR).CCS在每个级别上定义为:C3 / 4?=?1.82?cm2,C4 / 5?=?1.80?cm2,C5 / 6?= <1.84Ω·cm2,C6 /7≥=1.89Ω·cm2,C7 /T1≥=1.88Ω·cm2。 SCD 13?mm和IPD 22.5?mm的值与CCS相关,在每个水平上的敏感性和特异性为88-100 %%。 Logistic回归表明这些参数与CCS的存在之间存在显着相关性,每个水平的OR≥18。结论基于对大量成年骨骼样本的研究,我们在每个水平上定义了CCS。 SCD?<?13?mm和IPD?<?23?mm的值与各级CCS的存在密切相关...

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